AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Genetic Characterization of Patients With Arrhythmia-Induced Cardiomyopathy

Recruitingn/aAges 18 Years - anyAllHospital Universitario 12 de Octubre
💬

In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn about the genetic insights of arrhythmya-induced cardiomyopathy and its clinical prognosis. The main questions it aims to answer are: I. Does patients with arrhythmia-induced cardiomyopathy have a greater proportion of genetic mutations compared with other types of cardiomyopathy or general population? II. Have the genetics any prognostic impact in patients with arrhythmia-induced cardiomyopathy?

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Presence of atrial fibrillation or atrial flutter not self-limited. * Performance of a cardiac imaging test with systolic function analysis (echocardiogram, magnetic resonance, CT scan) during the clinical course of the arrhythmia, exhibiting a left ventricular ejection fraction (LVEF) \<50%. In order for the test to be representative, the maximum time between the performance of the imaging test and the rhythm control procedure will be 3 months, in the absence of intervening cardiovascular events that may have caused a variation in LVEF. In the event that the patient had a previously known LVEF \<50%, the change with respect to this attributable to tachyarrhythmia has to be ≥10%. * Signature of informed consent. * Ability to understand and accept participation in the study. Exclusion Criteria: * Refusal of informed consent. * Legal or juridical incapacity. * Age \<18 years. * Life expectancy less than 1 year. * Impossibility of a follow-up of at least 6 months. * Presence of a ventricular rate \>140 beats per minute, limiting the validity of imaging measurements. * Presence of known factors causing systolic ventricular dysfunction: * Prior cardiomyopathy diagnosis. * Severe mitral or aortic valve disease. * Non-revascularizable ischemic heart disease. * Context of peri-resuscitation cardiopulmonary care. * Abusive alcohol consumption, defined as \>80 grams of ethanol or \>7 standard alcoholic beverages per day. * Active treatment with chemotherapeutic agents or radiation therapy to the thorax. * Known infection with Trypanosoma cruzi, Borrellia burgdorferi or other infectious agent causing cardiomyopathy.
💊

What it tests

  • Not listed
📍

Where

4 sites
Ciudad Real General University Hospital
Ciudad Real, Spain
12 de Octubre University Hospital
Madrid, Spain
Albacete University Hospital Complex
Albacete, Spain
Ramón y Cajal University Hospital
Madrid, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy