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Cortisol and Obesity - A Vicious Cycle? Hypoglycemia After Bariatric Surgery - Association With Cortisol Metabolism?

Recruitingn/aAges any - anyAllEsbjerg Hospital - University Hospital of Souther…
NCT06896682 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn about how bariatric surgery affects the metabolism of cortisol. The main question it aims to answer is whether changes in cortisol contribute to the development of reactive hypoglycemia? 100 individuals who have previously undergone bariatric surgery, are planned to be included.

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📋 Eligibility rules (as published)
Inclusion Criteria: Participants must have undergone one of the following bariatric procedures at least 12 months prior: * Roux-en-Y gastric bypass * Gastric sleeve Exclusion Criteria * Pregnancy and breastfeeding * Nephrotic syndrome (kidney disease with protein loss in urine), liver cirrhosis, or severe malnutrition, as these conditions reduce cortisol-binding globulin (CBG) levels, affecting total cortisol concentration * Use of corticosteroid medications, such as prednisolone * Use of opiod-containing medication * Use of medications containing estrogen, such as hormone therapy for menopause * Known adrenal disease affecting cortisol metabolism, including autonomous cortisol production and Cushing's syndrome * Diabetes that does not require medical treatment * Previously diagnosed reactive hypoglycemia after bariatric surgery requiring medical treatment
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What it tests

  • Not listed
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Where

1 site
Esbjerg Hospital
Esbjerg, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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