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Spinal and Supraspinal Control in Chronic Ankle Instability

RecruitingNAAges 18 Years - 25 YearsAllAyca Yagcioglu
NCT06898554 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Ankle sprains are common sports injuries that often lead to chronic ankle instability (CAI). Patients with CAI experience deficits in neuromuscular control (NMC), including proprioception and strength. It is believed that damage to the ankle's ligament mechanoreceptors and the peroneal nerve after the initial ankle sprain can cause alterations in NMC, resulting in postural control and dynamic joint stability dysfunction. Inflammation related to recurrent ankle sprains may also contribute to neuromuscular impairments. Evidence suggests that bilateral postural control deficits occur after an ankle sprain, suggesting alterations in the central nervous system (CNS). Rehabilitation for CAI has been shown to lead to bilateral improvements in NMC, potentially due to neural alterations at both the spinal and supraspinal levels. Cross-education, which refers to the muscular crossed effect of unil

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📋 Eligibility rules (as published)
Inclusion Criteria: * Volunteering to participate in the study, * Being an athlete between the ages of 18-25, * Being a player in a field team sport such as basketball, volleyball, and handball, * Having a history of at least 2 significant grade II LAS diagnosed by a physician, * Related inflammatory symptoms, "giving away" sensation, obtaining a score ≤25 from the Cumberland Ankle Instability Tool (CAIT), * A score \<90% for the activities of daily living subscale and \<80% for the sport subscale from the Foot and Ankle Ability Measure, * Recurrent episodes of LAS of the injured ankle which occurred within at least 12 months. Exclusion Criteria: * Acute injury of lower extremity musculoskeletal structures in the last three months, * Orthopedic surgery in any of the lower extremities, * Bilateral ankle instability, * Vestibular or balance disorder
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What it tests

  • The structured balance training protocol
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Where

2 sites
Yeditepe University Koşuyolu Hospital
Istanbul, Turkey (Türkiye)
Yeditepe University
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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