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Activated Charcoal Use in Chronic Kidney Disease Patients

RecruitingPhase 2Ages 18 Years - anyAllMansoura University
NCT06906874 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Hyperphosphatemia management is initially based on restricting dietary phosphorus intake. Hyperphosphatemia is almost always seen in patients on dialysis and may contribute to progressive vascular calcification. Considering that activated charcoal is generally well-tolerated and may have a favorable side effect profile compared to conventional phosphate binders, it presents a promising alternative. Until now, no clinical trial has primarily investigated the effect of activated charcoal on hyperphosphatemia in dialysis patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Adult aged ≥18 years with ESRD. 2. Patients who had been on stable maintenance hemodialysis (3 times weekly) for at least 6 months. 3. Patients receiving phosphate binders according to standard protocols established by kidney disease: Improving Global Outcomes (KDIGO). Exclusion Criteria: 1. Severely malnourished (as diagnosed by the department's dietitian). 2. Treated with overnight dialysis. 3. Primary hyperparathyroidism or persistent serum levels of intact parathyroid hormone greater than 800 pg/mL.
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What it tests

  • Activated Charcoal
  • Phosphate Binders
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Where

1 site
Urology and Nephrology Center
Al Mansurah, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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