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Physiological Responses to Heat Stress During High-risk Events

Recruitingn/aAges 18 Years - anyAllUnited States Army Research Institute of Environm…
NCT06907225 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Exertional heat stroke (EHS) affects \~500 Military Personnel and over 100 Soldiers every year, and it is believed that these numbers are underreported. EHS is the most severe form of exertional heat illness (EHI) and can result in substantial, long-lasting organ damage, and even death in severe cases. Based on current knowledge and training needs, it is impossible to prevent every EHS - which shifts the focus from exclusively prevention to a combination of prevention, treatment, and enhancing recovery as much as possible. While many risk factors have been identified and there are adequate treatments available, biomarkers associated with heat stroke risk, recovery, and return-to-duty (RTD) remain largely unclear. The purpose of the proposed study is to enhance knowledge surrounding biomarkers of EHS and long-term health consequences that result from EHS. The investigators will recruit re

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📋 Eligibility rules (as published)
Inclusion Criteria: * Individuals (to include cis- and transgender males and females and nonbinary) 18 years of age or greater * Current military service (active, Reserve, or National Guard) * Currently participating in training Exclusion Criteria: * Females who are pregnant * Any individual currently on a physical profile that restricts running or foot marching * History of obstructive disease of the gastrointestinal tract including (but not limited to) diverticulosis, diverticulitis and inflammatory bowel disease, peptic ulcer disease, Crohn's disease, ulcerative colitis. * Scheduled MRI within 2 weeks after core temp pill ingestion * Known allergies to skin adhesive * Blood donation in the past 8 weeks
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What it tests

  • None-placebo
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Where

2 sites
Fort Novosel
Fort Novosel, United States
Field Study
Fort Jackson, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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