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A Study of Chios Mastic Water in Dyspepsia

RecruitingNAAges 30 Years - 60 YearsAllHarokopio University
NCT06909890 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Chios mastic is a natural product with strong antimicrobial, anti-inflammatory and antioxidant properties, and well-established benefits for dyspeptic disorders. The aim of the present study is to investigate the effectiveness of a natural aqueous extract of Chios mastic (mastic water), a by-product of Chios mastic processing, in the management of dyspepsia. This will be a 3-month randomized double-blind controlled clinical trial in adults with dyspepsia. Participants will be blindly randomized to an intervention group, which will receive 600 mL/d of a carbonated beverage enriched with Chios mastic water (0.2%), or a control group, which will receive 600 mL/d of an identical placebo beverage with no active ingredients. Participants will be evaluated in terms of anthropometric indices, lifestyle habits, severity of dyspepsia-related gastrointestinal symptoms, quality of life, as well as b

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 30-60 years old. * Body mass index of 20-35 kg/m2. * Presence of dyspepsia. Exclusion Criteria: * Presence of chronic diseases (e.g. diabetes mellitus, cancer, cardiovascular, hepatic, renal, respiratory, chronic inflammatory and psychiatric diseases). * Presence of other chronic gastrointestinal diseases (e.g. gastroesophageal reflux, inflammatory bowel disease and celiac disease). * Use of immunosuppressants, anti-inflammatories, antibiotics and corticosteroids. * Use of dietary supplements or other products with Chios mastic. * Excessive alcohol consumption (\>210 g and \>140 g of ethanol per week for men and women, respectively). * Currently on a weight-loss diet or recent (within 6 months) significant change in lifestyle habits. * Pregnancy or breast feeding (for women)
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What it tests

  • Chios mastic beverage
  • Placebo beverage
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Where

1 site
Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University of Athens
Kallithea, Greece
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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