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STI Testing to Enhance PrEP Use in Pregnancy

RecruitingPhase 3Ages any - anyFemaleBotswana Harvard AIDS Institute Partnership
NCT06919614 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The investigators are conducting a study in Botswana to see if offering STI testing along with expanded HIV prevention options (PrEP) helps more pregnant women start and continue using PrEP during and after pregnancy. Pregnant women (n=600) seeking antenatal care in Botswana will be enrolled and randomly assigned to receive the standard of care (standard STI assessment with no STI testing) versus STI testing for Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis during pregnancy and postpartum. The investigators' hypothesis is that providing STI testing alongside PrEP offer will encourage more women to start and continue using PrEP.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Pregnant and seeking antenatal care * Self-identifying as a cis-gender woman * Living without HIV * Not currently using PrEP * Planning to remain in the city/town of enrolment until 9 months post-delivery. * Planning to receive antenatal and postnatal care in the city/town of enrolment. * Willing and able to provide informed consent Exclusion Criteria: * Male gender * Not pregnant * Living with HIV * Currently using PrEP * Not planning to remain in the city/town of enrolment until 9 months post-delivery * Not planning to receive antenatal and postnatal care in the city/town to enrolment * Not able or willing to provide informed consent for participation
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What it tests

  • Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis testing
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Where

1 site
DHMT Clinics
Gaborone, Botswana
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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