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Assessment of Nutrient Absorption in Enterally Fed Post-intensive Care Unit Patients Using Bomb Calorimetry: do the Calories Stick

RecruitingNAAges 18 Years - anyAllUniversitair Ziekenhuis Brussel
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In plain words

What the trial is, and whether it could suit you

This study focuses on understanding how well patients who have recovered from an ICU stay absorb nutrients when receiving enteral (tube) feeding. Proper nutrition is crucial for recovery, but we don't fully understand how efficiently enteral feeding works in ICU survivors. The study will use advanced techniques like bomb calorimetry to measure the energy content of stool, and indirect calorimetry to measure patients' resting energy expenditure (REE). This will help assess the effectiveness of enteral feeding in these patients, providing valuable information about their metabolic needs and nutritional status. The study will also look into the environmental impact of enteral feeding, particularly food waste. By understanding how much of the nutrition is absorbed versus excreted, the study hopes to suggest more sustainable feeding practices and reduce unnecessary waste in hospitals. Key G

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * age of 18 years or older * minimum ICU stay of 7 days * fully dependent on enteral feeding (nasogastric or PEG-tube) * ability of the patient or representative to understand and sign written informed consent in Dutch, French or English Exclusion Criteria: * known inflammatory bowel disease * known malabsorptive gastrointestinal disease * history of small bowel resection * concomitant use of serotoninergic or sympathomimetic medications (oa. setrone, tryptans, antidepressants, methylphenidate, monoamine oxidase inhibitors, tramadol)
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What it tests

  • caloric intake measurement
  • stool sample collection
  • energy expenditure measurement
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Where

2 sites
UZ Brussel
Brussels, Belgium
UZ Brussel
Jette, Belgium
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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