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โ† Trials
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MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes

RecruitingPhase 2Ages 18 Years - 85 YearsAllMedical College of Wisconsin
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In plain words

What the trial is, and whether it could suit you

Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance. Preliminary data shows a single bout of ischemic conditioning or oral ingestion of an over-the-counter antioxidant supplement called MitoQ may improve vascular function and muscle activity in individuals post-stroke.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * 18 - 85 years of age * Cortical or sub-cortical stroke โ‰ฅ 6 months ago with residual hemiparesis * Able to give informed consent and follow 2-step command. * English Speaking Exclusion Criteria: * Unable to stand from chair without physical assistance from another person (able to use assistive device). * History of blood clots in the extremities or any condition in which compression of the thigh or transient ischemia is contraindicated (i.e., wounds in the leg). * Chronic lasting symptoms (\> 6 months) of severe COVID-19 (i.e., hospitalization) * History of head trauma or concussion within the past 6 months * Comorbid neurological disorder * Peripheral vascular disease * Myocardial infarction or arrhythmia in the previous year * Resting SBP โ‰ฅ180 mmHg or DBP โ‰ฅ 100 mmHg * Pregnant or breastfeeding. * Other significant medical condition likely to influence study or jeopardize safety as assessed by the Primary Investigator
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What it tests

  • Ischemic Conditioning
  • Antioxidant Supplement
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Where

1 site
Medical College of Wisconsin
Milwaukee, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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