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Revised Targets for Knee Radiofrequency Ablation

Recruitingn/aAges 18 Years - anyAllCentro Hospitalar Universitario do Algarve
NCT06934421 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This research team is doing a study to learn more about a new way to treat long-term knee pain caused by joint damage. They are using a treatment called radiofrequency ablation (RFA). This is a procedure where doctors use heat to stop certain nerves from sending pain signals. In this study, doctors will use ultrasound to guide a small needle to nerves around the knee, called genicular nerves. Then, they will apply heat to those nerves using radiofrequency energy to help reduce pain. The team created this new method based on recent studies of knee anatomy. They want to find out if this method can safely reduce pain and help people with knee joint damage move better. The study includes people who have moderate to severe knee damage and still have pain after trying medicine, physical therapy, or joint injections. Each person in the study will have the treatment once. The research team wi

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with chronic knee pain related to radiographic knee osteoarthritis, Kellgren-Lawrence (KL) grade III or IV, who are refractory to conservative treatment. (Refractoriness to conservative treatment is defined as: * Persistent pain and functional limitation after undergoing knee-targeted physiotherapy and analgesic medication in accordance with clinical guidelines for osteoarthritis \[e.g., paracetamol, nonsteroidal anti-inflammatory drugs, and other drugs as deemed appropriate by the treating physician\]; * Persistent pain and functional limitation after intra-articular corticosteroid injections or limited success with such interventions.) Exclusion Criteria: * Patients with previous knee arthroplasty * Patients who have undergone prior radiofrequency (RF) ablation * Significant psycho-emotional disorders * Addictive behaviors * Generalized pain * Nociplastic pain * Presence of a pacemaker * Presence of osteosynthesis material in the knee or adjacent anatomical regions
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What it tests

  • Ultrasound-Guided Genicular Nerve Radiofrequency Ablation
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Where

2 sites
Serviço de Medicina Física e de Reabilitação - Hospital de Faro - Unidade Local de Saúde do Algarve
Faro, Portugal
Serviço de Medicina Física e de Reabilitação - Hospital de São Francisco Xavier - Unidade Local de Saúde de Lisboa Ocidental
Lisbon, Portugal
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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