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OSNA Versus Ultrastaging to Detect Sentinel Lymph Node Metastasis in Endometrial Cancer

RecruitingNAAges any - anyFemaleFondazione Policlinico Universitario Agostino Gem…
NCT06935305 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Patients enrolled in the study will be randomized before surgery: in one study arm, the search for lymph node metastases in surgically removed sentinel lymph nodes will occur using the ultrastaging method (standard), while in the other arm it will be conducted using the OSNA method.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Histologically confirmed endometrial cancer * Apparent (pre-operative) FIGO stage I-II * Radical surgery * Attempt of SLN mapping Exclusion Criteria: * Uterine sarcoma (including endometrial stromal sarcoma) * Fertility sparing surgery * Dedifferentiated histology * Undifferentiated histology * Neoadjuvant therapy * Previous surgery to pelvic lymph nodes * Lymph nodes with short axis \>15 mm at pre-operative imaging
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What it tests

  • OSNA
  • Ultrastaging
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Where

1 site
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rome, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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