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ONO-4538 Study in Patients With Richter's Transformation

RecruitingPhase 2Ages 18 Years - anyAllOno Pharmaceutical Co., Ltd.
NCT06936943 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

Investigate the efficacy and safety of ONO-4538 in patients with Richter's transformation

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Histological diagnosis of diffuse large B-cell lymphoma (DLBCL)-type or Hodgkin lymphoma(HL)-type Richter's transformation with a history of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) * In the case of DLBCL-type Richter's transformation, refractory, intolerant or ineligible for treatment of DLBCL * Patients with measurable disease * Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 * Expected to survive for 90 days or more Exclusion Criteria: * Serious complications * Active multiple cancers * Active central nervous system (CNS) disease * History of allogeneic hematopoietic stem cell transplantation
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What it tests

  • ONO-4538
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Where

10 sites
Aichi Cancer Center
Nagoya, Japan
Kyusyu University Hospital
Fukuoka, Japan
Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital
Hiroshima, Japan
Hokkaido University Hospital
Sapporo, Japan
Kyoto University Hospital
Kyoto, Japan
Tohoku University Hospital
Sendai, Japan
Niigata University Medical & Dental Hospital
Niigata, Japan
Kindai University Hospital
ลŒsaka-sayama, Japan

โ€ฆand 2 more on ClinicalTrials.gov.

๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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