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Mechanisms of Deep Transcranial Magnetic Stimulation in Enhancing Cognitive-Behavioral Therapy for Anorexia Nervosa

RecruitingNAAges 18 Years - 35 YearsFemaleShanghai Mental Health Center
NCT06942858 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if dTMS targeting the ACC can be used to rapidly and effectively treat AN. A randomized controlled study design is adopted, in which patients with AN are divided into the CBT+dTMS treatment group and CBT+pseudostimulation group by 1:1 randomization, followed by a 6-week intervention and a half-year follow-up to clarify whether CBT combined with dTMS is superior to single CBT treatment for AN.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Inclusion Criteria: * Female, aged 18-35 years, right handedness. * Above primary education. * Meet the diagnostic criteria of AN in DSM-V, and13.0 kg/m2 ≤ body mass index (BMI)\<18.5 kg/m2. * No systemic nutritional therapy, psychiatric medication or any form of psychotherapy have been received within 1 month before enrollment. * Able to understand the nature of this study and sign an informed consent form. Exclusion Criteria: * Diagnosed with a DSM-5 disease other than anorexia nervosa, or at high risk of suicide, strong impulsive behavior as well as anti-social behavior. * With severe physical or cognitive impairment. * Not able to undergo MRI. * Considered unsuitable for enrollment in this clinical trial for other reasons.
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What it tests

  • Deep transcranial magnetic stimulation
  • cognitive behavior therapy
  • Sham deep transcranial magnetic stimulation
  • Basic treatment
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Where

1 site
Shanghai Mental Health
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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