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โ† Trials
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Immunological Aspect of Thrombotic Thrombocytopenic Purpura (TTP)

Recruitingn/aAges 18 Years - anyAllUniversity Hospital, Rouen
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In plain words

What the trial is, and whether it could suit you

The general objective of the proposed project is to characterise phenotypically and functionally ADAMTS13-specific memory B lymphocytes and autoreactive T lymphocytes, in particular follicular helper T lymphocytes, in the acute phase of the disease, but also during its progression after treatment. The aim is to highlight their contribution to the initial pathogenic process, their evolution under treatment, and also their involvement in patients who are refractory to immunosuppressive therapies and during relapses. The aim of this project is to identify early phenotypic or functional parameters that are predictive of relapse and that can be used for personalised optimisation of treatment to maintain remission.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * age over 18 * patients with TTP at any stage of diagnosis (acute phase, lasting remission or not, relapse) * patients undergoing internal medicine at Rouen University Hospital * people who have read and understood the information letter * membership of a social security scheme Exclusion Criteria: \- a person deprived of liberty by an administrative or judicial decision or a person placed under court protection/guardianship or guardianship
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What it tests

  • Not listed
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Where

1 site
University Rouen Hospital,
Rouen, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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