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The Role of Melatonin as an Adjuvant Therapy in Childhood Pneumonia

RecruitingPhase 1, Phase 2Ages 1 Month - 12 YearsAllMian Muhammad Hassan Ahmed
NCT06949904 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to compare the mean length of hospital stay between children with pneumonia receiving melatonin as an adjuvant therapy and those receiving standard of care alone. The hypothesis is that combining oral melatonin with standard treatment can reduce the length of hospital stay as compared to standard of care alone. The control group will receive standard treatment (antibiotic) while the intervention group will receive standard treatment plus melatonin for 14 days.

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📋 Eligibility rules (as published)
Inclusion Criteria: * 1 month to 12 years * Both genders * Patient diagnosed as having pneumonia or severe pneumonia according to WHO definition Exclusion Criteria: * Hospitalized within 14 days prior to the study * Known TB exposure * Active varicella or herpes simplex infection * Allergy to the study medication * Currently taking melatonin * Any non pneumonia acute medical illness which requires antibiotic treatment as per local standard of care * Galactose intolerance, the lapp-lactase deficiency or glucose-galactose malabsorption * Significant co-morbid disease: lung, cardiac, immune, liver, endocrine, neurological or psychiatric
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What it tests

  • Melatonin
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Where

1 site
Pakistan Institute of Medical Sciences
Islamabad, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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