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HYPERtension Reduction Through WALKing Stairs Versus Brisk Walking

RecruitingNAAges 35 Years - anyAllKarolinska Institutet
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In plain words

What the trial is, and whether it could suit you

This clinical trial investigates whether incorporating stair walking into daily routines improves physical health in adults at risk of lifestyle-related conditions such as hypertension, type 2 diabetes, and cardiovascular disease. Participants will be randomized into three groups: (1) stair walking combined with brisk walking, (2) brisk walking alone, and (3) a control group receiving standard lifestyle advice without specific exercise instructions, stratified by age (\<65 y/o, v \>=65) and site. The primary objective is to assess whether the combination of stair and brisk walking leads to greater reductions in systolic blood pressure compared to brisk walking alone or standard care. Secondary outcomes include changes in cardiometabolic risk factors. Participants in the stair walking group will be instructed to climb ≥250 steps per day (\~5.5 minutes/day or \~37.5 minutes/week), or com

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📋 Eligibility rules (as published)
Inclusion Criteria Men and women aged 35 years or older with increased cardiometabolic risk, defined by all of the following: 1. Clinically confirmed hypertension, with or without antihypertensive treatment, as documented in the Electronic Health Record (EHR). 2. Overweight or obesity, defined as BMI between 27 and 40. 3. Physically inactive lifestyle, defined as either: * Light intensity or inactive category on the Stanford Brief Activity Survey (SBAS), or * Light intensity or inactive category in the physical activity section of the Swedish National Board of Health and Welfare Lifestyle Questionnaire. Exclusion Criteria Medical contraindications to physical activity (based on FYSS 2021, p. 182): * Severe, symptomatic aortic stenosis * Acute pulmonary embolism, myocarditis, pericarditis, or systemic infection (e.g., fever, muscle pain, lymphadenopathy) * Suspected or known aortic dissection * Severe hypertension (Grade 3: SBP \>180 mmHg or DBP \>110 mmHg), regardless of symptoms * Unstable coronary artery disease (including unstable angina, suboptimally treated stable angina, or recent myocardial infarction \<8 weeks) * Symptomatic, uncontrolled arrhythmia * Symptomatic, uncontrolled heart failure Other exclusion criteria: * Implanted pacemaker or ICD * Pregnancy * Smartphone incompatibility with Fitrockr© app (iOS \<16 or Android OS \<10) * Inability to understand Swedish or English * Any condition that may interfere with protocol compliance (e.g., severe mental illness or cognitive impairment) * Inability to walk stairs
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What it tests

  • Stair and brisk walking combined
  • Brisk walking
  • Standard care
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Where

4 sites
Karolinska Universitetssjukhuset Huddinge
Stockholm, Sweden
Liljeholmen Primary Care Center
Stockholm, Sweden
Södersjukhuset
Stockholm, Sweden
Södertälje sjukhus
Stockholm, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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