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Vagal Stimulation Therapy and Preeclampsia

RecruitingNAAges 18 Years - anyFemaleFundación Internacional René Mey
NCT06953115 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Preeclampsia is one of the most common and serious complications of pregnancy, affecting both the mother and baby. It is a condition characterized by high blood pressure and can lead to severe complications, including neurological issues and reduced blood flow to the placenta. Preeclampsia is responsible for a significant number of maternal and perinatal deaths worldwide, with an estimated 14% of maternal mortality in Mexico linked to this condition. Recent research suggests that disruptions in the body's autonomic nervous system, specifically the balance between the sympathetic and parasympathetic systems, play a role in the development of preeclampsia. The vagus nerve, which is part of the parasympathetic system, has been shown to regulate inflammation and blood pressure. Stimulating this nerve through pharmacological, magnetic, electrical, or physical therapy techniques has shown pro

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📋 Eligibility rules (as published)
Inclusion Criteria: * Outpatient female patients over 18 years old, attending their first appointment and seen in the obstetrics outpatient clinic at the Regional General Hospitals of IMSS Jalisco, with a pregnancy complicated by confirmed mild preeclampsia. * No prior treatment. * Willing to participate by signing an informed consent form. Exclusion Criteria: * Patients with chronic hypertension. * Concomitant organ dysfunction. * Immunological diseases. * Patients with severe preeclampsia or chronic conditions concomitant with pregnancy. * Patients with gestational trophoblastic disease requiring uterine evacuation or choriocarcinoma associated with hypertension.
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What it tests

  • Vagal stimulation physiotherapy with trigger point release
  • Positional Release Therapy
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Where

4 sites
Unidad de Investigación Biomédica 02, UMAE HE CMNO IMSS
Guadalajara, Mexico
Hospital General de Zona 110, IMSS
Guadalajara, Mexico
Hospital General de Zona 46, IMSS
Guadalajara, Mexico
Hospital General de Zona 180, IMSS
Tlajomulco de Zúñiga, Mexico
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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