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Assessing the Effects of a Multisectoral Agricultural Intervention on the Reproductive and Sexual Health of Adolescent Girls and Young Women

RecruitingNAAges 15 Years - anyAllUniversity of California, San Francisco
NCT06953310 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In Kenya, HIV incidence among adolescent girls and young women (AGYW) ages 15-24 years is 1-2 per 100 person-years and approximately 30% of AGYW have had at least one sexually transmitted infection (STI). Kisumu and Migori counties in Western Kenya have some of the highest HIV/STI incidence in the country. Food insecurity (FI) and poverty are also highly prevalent in Western Kenya. FI and poverty are important drivers of vulnerability to HIV and STIs among AGYW. Poverty alleviation interventions have the potential to reduce STIs and HIV risk among AGYW but, to date, these interventions have reported mixed findings on HIV/STI outcomes, have been primarily targeted at the individual level, and none have focused on agriculture or FI. Therefore, there remains a critical need to develop sustainable, multi-level, economic and FI interventions that improve AGYW STI/HIV prevention outcomes. Our

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📋 Eligibility rules (as published)
Inclusion Criteria: Adolescent Girls and Young women (AGYW): * AGYW assigned female at birth * Between 15-19 years of age at enrollment * Attending the selected schools with at least 18 months remaining of schooling * STI-uninfected and not pregnant at baseline * Has an adult caregiver willing to participate * Demonstrates moderate to severe FI based on the Household Food Insecurity Access Scale (HFIAS), and/or malnutrition (BMI less than two standard deviations below the mean for age-specific BMI Caregiver: * At least 18 years old. * At least 1 AGYW aged 15-19 years old attending the selected schools * household has access to farming land * household has available surface water in the form of lakes, rivers, ponds, or shallow wells (home is 200m from permanent water source) Exclusion Criteria: * AGYW or adult caregivers who have inadequate cognitive and/or hearing capacity to complete planned study procedures * AGYW or adult caregivers who do not speak Dholuo, Kiswahili, or English * Married AGYW and those who serve as heads of households * AGYW who are pregnant at screening Adolescent girls who test positive for gonorrhea or chlamydia at screening will be invited to re-screen at least 14 days after receiving treatment and will be eligible to enroll if they have a confirmatory negative STI test.
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What it tests

  • Shamba Maisha
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Where

1 site
Kenya Medical Research Institute (KEMRI)
Kisumu, Kenya
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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