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The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema

RecruitingPhase 4Ages 18 Years - 65 YearsAllKing Abdulaziz University
NCT06953440 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This clinical trial aims to investigate whether dexamethasone decreases edema and trismus in adults undergoing lower third molar surgical extraction. The main question it aims to answer is: Does dexamethasone submucosal injection have a positive impact on trismus and edema after third molar surgery compared to conventional postoperative prescription? Participants will: * Be administered with dexamethasone submucosal injection or a placebo after the surgery. * Visit the clinic three times the week after the extraction for follow-up.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with impacted lower third molars requiring surgical extraction. * Adults over the age of 18 years old. * American Society of Anaesthesiologists (ASA) 1, and ASA 2 Exclusion Criteria: * Patients with preoperative intraoral or extraoral swelling. * Patients requiring simple extraction (Class I group A according to Pell and ---Gregory classification). * Patients with uncontrolled systemic disease such as uncontrolled diabetic - patients. * Patients who are allergic to corticosteroids. * Patients who are contraindicated to use corticosteroids such as uncontrolled diabetic patients, and osteoporotic patients. * Patients who require extraction of additional teeth at the same visit.
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What it tests

  • Dexamethasone Sodium Phosphate Injection
  • Normal Saline (Placebo)
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Where

1 site
King Abdulaziz University, Faculty of Dentistry
Jeddah, Saudi Arabia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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