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Restricted Versus Liberal Fluid Intake for Prevention of Bronchopulmonary Dysplasia

RecruitingNAAges 8 Days - anyAllUniversity Children's Hospital Basel
NCT06954142 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this study is to determine whether restricted fluid intake (135 ±5 mL/kg/day) compared to liberal fluid intake (165 ±5 mL/kg/day) from day 8 of life reduces the incidence of bronchopulmonary dysplasia (BPD) at 36 weeks postmenstrual age or prior death in preterm infants born \<30 weeks gestational age.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Hospitalised preterm infants born before 30 weeks 0 days gestation * Signed informed consent for further research use of health-related data Exclusion Criteria: * congenital malformations * diseases likely to affect life expectancy, lung function, fluid strategy, or neurodevelopment * renal disease requiring fluid management outside the clinical standard of care * congenital heart disease not including patent ductus arteriosus (PDA)
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What it tests

  • Fluid restriction
  • Liberal fluid intake
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Where

9 sites
Kantonsspital Aarau AG, Klinik für Kinder u. Jugendliche
Aarau, Switzerland
University Children's Hospital Basel (UKBB)
Basel, Switzerland
Inselspital Bern, Kinderklinik
Bern, Switzerland
Kantonsspital Graubünden, Departement Kinder- und Jugendmedizin
Chur, Switzerland
Hôpitaux universitaires de Genève (HUG), Service de Néonatologie et Soins Intensifs
Geneva, Switzerland
Centre hospitalier universitaire vaudois (CHUV) - Service de néonatologie
Lausanne, Switzerland
Luzerner Kantonsspital, Kinderspital
Lucerne, Switzerland
Ostschweizer Kinderspital & Neonatologie und Frauenklinik KSSG
Sankt Gallen, Switzerland

…and 1 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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