🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study

Recruitingn/aAges 18 Years - anyAllSied Kebir
NCT06954636 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The study aims to investigate the prognostic significance of olfactory function in patients with glioblastoma. We are examining olfactory function at various points during therapy and correlating the results with survival data. In addition, neurocognitive tests will be carried out to correlate the results of olfactory function with the patient's cognitive abilities. Investigations into the quality of life and psychological condition of the patients are also performed. In addition to the cohort of glioblastoma patients, there is a control cohort without tumor disease in which the olfactory testing is also carried out in order to have a comparison.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * At least 18 years of age * Newly-diagnosed glioblastoma (IDH wild-type) * Never received prior chemotherapy * Never received radiotherapy to the head or neck before * KPS ≥ 70 * No history of severe head or brain trauma requiring ICU admission or classified as Glasgow Coma Scale grade 3 * No respiratory infection at the time of inclusion * No significant aphasia Exclusion Criteria: * Presence of Neurodegenerative diseases (e.g. Parkinson's disease, Alzheimer's disease, Huntington's disease, Korsakoff's syndrome, Pick's disease, Shy-Drager syndrome) * History of invasive tumors or surgery in the head or neck area, except for surgeries for non-invasive skin tumors (e.g. basal cell carcinomas) * Permanent olfactory impairment following infections (e.g., influenza, coronavirus) * Conditions that, in the examiner's judgment, could interfere with the participant's study compliance (e.g., schizophrenia) * Language barriers likely to interfere with participation or comprehension of study procedures.
💊

What it tests

  • olfactory testing (threshold and identification test)
📍

Where

2 sites
University Hospital Essen, Department of Neurology, Division of Clinical Neuro-Oncology
Essen, Germany
Department of Neurosurgery
Münster, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy