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Magnesium Sulfate in Addition to Bupivacaine in Ultrasound-guided Transmuscular Quadratus Lumborum Block for Post-Operative Analgesia After Total Hip Arthroplasty

RecruitingPhase 2, Phase 3Ages 18 Years - anyAllTanta University
NCT06956950 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this clinical trial is to evaluate the efficacy of adding magnesium sulfate to bupivacaine in ultrasound-guided transmuscular quadratus lumborum block for postoperative analgesia in adult patients underdoing hip arthroplasty. The main questions it aims to answer are: * Does Magnesium sulphate lower Pain score (VAS) postoperatively. * Does Magnesium sulphate lowerTotal opioid consumption postoperatively. and What side effects do participants have when taking Magnesium sulphate? Researchers will compare Magnesium sulphate to a placebo (a look-alike substance that contains no drug) to see if Magnesium sulphate works to lower pain score. Participants will: * Take with have ultrasound-guided transmuscular quadratus lumborum block after surgery using bupivacaine with Magnesium sulphate or with placebo * Followed up 48 hours postoperatively to monitor pain score or any reported si

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years. * American Society of Anesthesiology (ASA) class I-III * Undergoing hip arthroplasty . Exclusion Criteria: * Patient refusal. * Body mass index (BMI) \> 40 Kg/m2. * Allergy to local anesthetics or magnesium sulphate. * coexisting coagulopathy. * Local infection at puncture site. * Severe renal impairment ( eGFR \< 30 ml/min)
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What it tests

  • Bupivacaine + Magnesium sulfate
  • Bupivacaine + saline
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Where

1 site
Faculty of medicine
Tanta, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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