🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course

RecruitingNAAges 18 Years - anyAllUnited States Department of Defense
NCT06957067 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Investigators' overall objective is to compare methods of identifying individuals who may be experiencing challenges in Cognitive Processing Therapy (CPT) and compare methods of intervening to optimize treatment retention and outcomes. Investigators' specific aims are: 1. to determine whether the use of CPT skills versus collaboratively considering switching to Present Centered Therapy (PCT) is more effective in improving outcomes for individuals experiencing challenges with CPT. Outcomes include post-traumatic stress disorder (PTSD) severity \[primary\], depression, functioning, and treatment retention; 2. to compare two approaches to identifying individuals in CPT in need of additional support during treatment; 3. to study the barriers and facilitators of implementing these intervention strategies. Finally, exploratory aims will examine the stability of differences between treatment

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Veterans interested in outpatient VA psychotherapy for PTSD * Meets DSM-5 criteria for PTSD * Be able to provide informed consent * Be willing to be randomized * Agree to not receive non-study psychotherapy for PTSD during study treatment (case management, supportive therapy/group, and concurrent substance use treatment are allowable) Exclusion Criteria: * Severe cognitive impairment * Current suicidal or homicidal intent with a specific plan * Uncontrolled psychotic or manic symptoms * A psychiatric medication change in the past month * A severe SUD as diagnosed by the DSM-5
💊

What it tests

  • CPT Skills
  • Cognitive Processing Therapy
  • Present Centered Therapy
  • Shared Decision Making
  • Measurement Based Care
📍

Where

4 sites
VA Phoenix Health Care System
Phoenix, United States
New Orleans VA Medical Center
New Orleans, United States
Ralph H. Johnson VA Health Care System (Charleston VA)
Charleston, United States
VA Houston Healthcare System
Houston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy