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Analysis of Salivary Proteins in Young Children as an Device to Improve Caries Risk Assessment

Recruitingn/aAges 3 Years - 3 YearsAllKarolinska Institutet
NCT06957509 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn if the composition of salivary proteins in 3-year-old children, from communities with documented varying caries risks, can be used to identify future diagnostic predictors for caries risk. The main question to answer is: • Can the host´s salivary protein profile (expression and abundance) show a correlation with the caries prevalence between the individuals in the different study cohorts? Two cohorts of children with different documented demographic characteristics in the region of Stockholm (Sweden) will be examined. Participants will be asked to provide saliva samples and undergo clinical oral examinations conducted by trained dental practitioners.

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📋 Eligibility rules (as published)
Inclusion Criteria: * 3-year-old children residing in the areas served by Folktandvården Danderyd and Järva, respectively * Written consent, signed by both parents (guardians) Exclusion Criteria: * children older than three years * medication intake, and antibiotic use at the time of examination * children who have consumed food, drink, or used oral hygiene products within 2 hours before the dental visit * children who appear uncooperative during saliva sampling
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What it tests

  • Not listed
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Where

1 site
Folktandvården Stockholms län AB
Stockholm, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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