Long Term Clinical Outcome After Arthroscopic Rotator Cuff Repair Augmentation With Autologous Microfragmented Lipoaspirate Tissue

Inclusion Criteria: * Age \> 18 years * Full-thickness supraspinatus and infraspinatus tendon tears (C1, C2, and C3 according to the SCOI classification) * Indication for arthroscopic rotator cuff repair * Informed consent to participate in the study * Informed consent to participate for the duration of the study Exclusion Criteria: * Partial rotator cuff tendon tears (A1, A2, A3, B1, B2, and B3 according to the SCOI classification) * Massive rotator cuff tear (C4 according to the SCOI classification) * Subscapularis tendon tear (grade III, IV, or IV according to Lafosse classification) * Associated anterior, posterior, or multidirectional shoulder instability * Indication for repair of a SLAP lesion of the biceps anchor * Grade III or IV muscle atrophy of the supraspinatus and infraspinatus tendons (according to Goutallier or Fuchs classification) * Intra-articular hyaluronic acid or corticosteroid infiltration within 3 mo from the planned surgical procedure * Medical comorbidities contraindicating arthroscopic shoulder surgery * Local (shoulder, abdominal region, gluteal region) or systemic infection, osteomyelitis, or sepsis * Diabetes mellitus, untreated thyroid disease, chronic kidney disease, rheumatoid arthritis * Immunodeficiency * Chronic disorders involving coagulation, platelet aggregation, or severe coagulopathy * Severe cardiovascular disease * Stroke or acute cardiovascular event within 6 mo from the planned surgical procedure * Weight loss for any cause .30 kg in 12 mo or .10 kg in 12 mo without a cause * Eating disorders or body dysmorphic disorder * Varices, phlebitis, or scars next to the planned adipose tissue harvesting site * Alcohol/drug addiction or psychiatric disease compromising compliance with postoperative protocols * Pregnancy or breastfeeding women * Informed consent not accepted