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โ† Trials
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Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate

RecruitingNAAges 45 Years - 85 YearsAllShandong University
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In plain words

What the trial is, and whether it could suit you

Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection rate, but considering the long withdrawal time of the endoscope and the resulting increase in time and cost. Linked-color imaging (LCI) is a newly developed image-enhanced endoscopy technology. It relies on wave length optimization of three colors (red, green, and blue) to make the lesions appear fuller. LCI improves the visibility of colorectal adenomas and polyps and may increase the detection rate of lesions. In order to explore the clinical application value of Linked-color imaging endoscopy, we performed a prospective, randomized controlled trial to compare adenoma detection rate of Linked-color imaging endoscopy and indigo carmine chromoendoscopy.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Age between 45 and 85 years 2. Patients with a history of colorectal adenoma 3. Patients whose first-degree relatives have a history of colorectal cancer or colorectal adenoma 4. Patients with gastrointestinal symptoms (abdominal pain, bloody stool, chronic diarrhea or constipation, Unexplained anemia or weight loss; 5. Patients with positive Fecal Immunochemical Test Exclusion Criteria: 1. Patients with pregnancy, inflammatory bowel disease, familial adenomatosis polyposis, suspected CRC; intestinal obstruction, coagulopathy 2. Patients with aspirin, clopidogrel or other anticoagulants/ antiplatelet drugs intake within 7 days 3. Patents previous colorectal resection 4. Patients with failed cecal intubation 5. Patients with inadequate bowel preparation quality (BBPSโ‰ค5) 6. Patients who refuse to participate or to provide informed consent
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What it tests

  • Chromoendoscopy with indigo carmine solution spray
  • Linked-color imaging endoscopy
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Where

1 site
Qilu Hospital of Shandong University
Jinan, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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