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Effectiveness of Ventilation Modes in Intensive Care: A Comparison of Mandatory Minute Ventilation and Synchronized Intermittant Mandatory Ventilation Using Bioelectrical Impedance Tomography

Recruitingn/aAges 18 Years - anyAllHarran University
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In plain words

What the trial is, and whether it could suit you

Synchronized Intermittent Mandatory Ventilation (SIMV) is a commonly used ventilatory mode available in many modern ventilators, frequently applied in intensive care units for patients requiring invasive mechanical ventilation. SIMV delivers a preset tidal volume or pressure at a predetermined respiratory rate and synchronizes with the patient's spontaneous breathing efforts, thereby enhancing patient-ventilator interaction and contributing to rehabilitation. Mandatory Minute Ventilation (MMV) is a hybrid mode combining features of SIMV and Pressure Support Ventilation (PSV), guaranteeing a preset minute ventilation (tidal volume × respiratory rate). It synchronizes support based on the patient's spontaneous efforts and compensates in cases of insufficient minute ventilation. Electrical Impedance Tomography (EIT) is a non-invasive, radiation-free imaging technique that enables real-tim

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years Intubated and receiving invasive mechanical ventilation Hemodynamically stable (no vasopressor support) FiO₂ ≤ 60% PEEP ≤ 8 cmH₂O Not receiving neuromuscular blocking agents Able to tolerate switching between SIMV and MMV modes Exclusion Criteria: Pregnant or breastfeeding patients Patients with neuromuscular diseases affecting respiratory drive Unstable hemodynamics or ongoing need for vasopressors Patients requiring high PEEP (\>8 cmH₂O) Patients with DNR (do not resuscitate) status Participation in another interventional study \-
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What it tests

  • No investigational intervention
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Where

1 site
Harran University Faculty of Medicine, Department of Anesthesiology and Reanimation
Sanliurfa, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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