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Outcomes Following Limb Sparing Surgery for Soft Tissue Sarcoma

Recruitingn/aAges 18 Years - anyAllAmsterdam UMC
NCT06962072 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to assess body image, health-related quality of life (QoL), and functioning (gait function, joint function, and walking ability) in patients after resection of localized soft tissue sarcoma (STS) of the extremities. A secondary objective is to assess the influence of different variables (e.g., radiotherapy, ethnicity, etc.) on body image, health-related QoL, and functioning. Patients who underwent a surgical resection at the Amsterdam UMC between 2010 and 2021 will be approached to participate in the study. Participants will complete four questionnaires and undergo a physical examination. Additionally, they will have a 3D gait analysis, a 6-minute walk test with gas analysis, and a muscle strength assessment. Furthermore, muscle volume change will be evaluated on pre- versus postoperative MRI scans.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Treated with surgical resection for primary non-metastatic extremity STS at the Amsterdam UMC between 2010-2021. * Being able to visit the Amsterdam UMC, location AMC once or twice. * Pregnant patients must agree to be scheduled 5 months after their pregnancy ends. Exclusion Criteria: * Patients who cannot maintain 6 minutes of walking will be excluded from the 6-minute walk test.
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What it tests

  • Surgical resection with or without radiotherapy and/or chemotherapy
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Where

1 site
Amsterdam UMC
Amsterdam, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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