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RAB Versus Ultrathin Bronchoscopy With VBN in the Diagnosis of PPNs

RecruitingNAAges 18 Years - anyAllShanghai Chest Hospital
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to evaluate whether the diagnostic yield of robotic-assisted bronchoscopy is not inferior to that of the virtual bronchoscopic navigation combined with ultrathin bronchoscopy.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age ≥ 18 years, regardless of gender; 2. Patients with peripheral lung nodules of suspected malignancy on chest CT who require non-surgical biopsy; 3. Patients who voluntarily consent to undergo bronchoscopy and meet the requirements for the bronchoscopy; 4. Patients should understand the purpose of the trial, demonstrate good compliance with the examinations and follow-ups, and voluntarily participate in the clinical trial and sign the informed consent form. Exclusion Criteria: 1. Presence of contraindications for bronchoscopy, including: active massive hemoptysis; recent myocardial infarction or unstable angina; severe cardiac or pulmonary dysfunction; severe hypertension and arrhythmias; uncorrectable bleeding tendencies or severe coagulation disorders (such as platelet count \<60×10\^9/L), uremia; severe pulmonary artery hypertension; severe superior vena cava syndrome; intracranial hypertension; acute cerebrovascular events; aortic dissection or aneurysm; multiple bullae; extreme systemic exhaustion; 2. Patients with pure ground-glass nodules suspected of malignancy on chest CT; 3. Female patients who are breastfeeding, pregnant, or planning pregnancy; 4. Patients with electromagnetic active implantable medical devices; 5. Subjects allergic to anesthetics; or with a history of multiple severe allergies, hereditary allergy history; 6. Those who have participated in or are currently participating in drug clinical trials within 3 months before screening, or have participated in other medical device clinical trials within 30 days; 7. Any other conditions deemed unsuitable for participation in this clinical trial by the investigator.
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What it tests

  • Robotic bronchoscopy system
  • Ultrathin bronchoscope combined with virtual bronchoscopic navigation
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Where

5 sites
Shandong Public Health Clinical Center
Jinan, China
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, China
Shanghai Chest Hospital
Shanghai, China
Zhongshan Hospital,Fudan University
Shanghai, China
Sir Run Run Shaw Hospital , affiliated with the Zhejiang University School of Medicine
Hangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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