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High-definition Surface Electromyography Markers for the Diagnosis and Monitoring of Sarcopenia

RecruitingNAAges 75 Years - anyAllAssistance Publique - Hôpitaux de Paris
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In plain words

What the trial is, and whether it could suit you

Sarcopenia is a progressive and generalised skeletal muscle disorder involving the accelerated loss of muscle mass and function that is associated with increased adverse outcomes including falls, functional decline, frailty, and mortality. In this project, the high-definition surface electromyography technology (HD-sEMG) signals will be analysed to extract features/ markers for the diagnosis of sarcopenia. This is a multicentric, descriptive, cross-sectional, parallel group study to develop a new diagnostic method. It is planned to include 846 people aged 75 years and over hospitalized in the acute geriatric or rehabilitation wards and suspected of sarcopenia (Score ≥4 on the SARC-F screening questionnaire). The inclusion duration will be 18 months and adding a 3-month patient follow-up. The total study duration will be 21 months. Patients will have their body composition using bioimped

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Patient aged 75 years and over * Score ≥4 on the SARC-F screening questionnaire * Enrolled in a social security plan (no AME) * Informed and consenting patient Exclusion Criteria: * BMI ≥30 kg/m2 * Severe psychiatric pathology or severe cognitive disorders that do not allow the performance of examinations * Patients who are dependent for all acts of daily life * Patients with a very short life expectancy \<3months * Pace maker * Recent fracture or trauma of the preventing dynamic measurement of HD-sEMG recording * Bilateral hip prosthesis * Skin problem that may interfere with the recording of surface EMG activity * Skin allergies to plasters * Allergies to electrode materials (acrylate) * Patient under legal protection * Patient on state medical aid (AME : Aide Médicale d'Etat)
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What it tests

  • HD-sEMG
  • Quadriceps muscle ultrasound
  • IPAQ Physical Activity Questionnaire
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Where

11 sites
Hôpital Corentin Celton, APHP
Issy-les-Moulineaux, France
Hôpital Corentin Celton, APHP
Issy-les-Moulineaux, France
Hôpital Charles Foix, APHP
Ivry-sur-Seine, France
Hôpital Charles Foix, APHP
Ivry-sur-Seine, France
Hôpital Charles Foix, APHP
Ivry-sur-Seine, France
Unité d'Explorations fonctionnelles du sujet âgé - Hôpital Charles Foix
Ivry-sur-Seine, France
Hôpital Rothschild, APHP
Paris, France
Hôpital Rothschild, APHP
Paris, France

…and 3 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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