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Evaluation of Microbial and Endocrinological Parameters in Dialysis Patients With Sepsis

Recruitingn/aAges 18 Years - anyAllWestern Galilee Hospital-Nahariya
NCT06963853 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective study aims to evaluate the diagnostic value and reliability of blood cultures obtained from different sources-central venous catheter (CVC), dialysis machine, and peripheral vein-in hemodialysis patients with suspected catheter-related bloodstream infections (CRBSIs). By comparing the timing and rates of bacterial growth from each site, the study seeks to identify the most accurate and timely method for diagnosing bloodstream infections in this patient population. In addition, the study will assess the dynamics of parathyroid hormone (PTH) levels during acute infections. Specifically, it will investigate whether a significant drop in PTH levels-and the rate of recovery following infection-correlates with adverse outcomes such as infectious complications, cardiovascular morbidity, or 90-day mortality. These findings may offer valuable prognostic insights and support impr

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📋 Eligibility rules (as published)
Inclusion Criteria: hemodialysis patients over the age of 18 who are hospitalized at the Galilee Medical Center due to sepsis and have provided written informed consent to participate in this study. \- Exclusion Criteria: • Patients with cognitive impairment who are unable to provide informed consent. \-
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What it tests

  • Blood cultures will be obtained from three sources: 1. The central venous catheter (CVC), 2. The dialysis machine circuit, and 3. A peripheral vein
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Where

1 site
Galilee Medical Center
Nahariya, Israel
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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