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To Determine Whether it is Feasible to Treat Patients Requiring Urgent Radiotherapy Diagnosed With Metastatic Cord Compression (MSCC) on the Magnetic Resonance Linear Accelerator (MRL) in a Single Appointment and Compare it to the Standard of Care Radiotherapy Pathway

RecruitingNAAges 18 Years - anyAllThe Christie NHS Foundation Trust
NCT06965101 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to understand whether the Magnetic Resonance Linear Accelerator (MRL) could expedite Radiotherapy treatment for Metastatic Cord Compression (MSCC) by removing the need for a planning CT (pCT) scan prior to treatment. Radiotherapy will be delivered in one appointment on the MRL and compared to the standard of care of two appointments: a CT scan and a Radiotherapy appointment. The main questions it aims to answer are: * Can the MRL deliver successful treatment of MSCC in a single 1-hour appointment? * Can the MRL treat participants within 24 hours from the doctor's decision to treat? * Did it take less time from consent to completion of treatment when patients were treated on the MRL? * Do the questionnaire scores reflect satisfaction with treatment on the MRL? Researchers will compare treatment on the MRL in one appointment to a group receiving standar

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📋 Eligibility rules (as published)
Inclusion Criteria: * Confirmed Diagnosis of MSCC * Referred for an 8Gy, Single Fraction of Radiotherapy * 18 years or older. * Able to give informed consent in writing or verbally. * Willing to complete patient experience questionnaire * Willing to have the research team review their case notes for up to 1 year following Exclusion Criteria: * Participant does not have capacity and cannot give informed consent. * Any evidence of significant clinical disorder or laboratory finding which, in the opinion of the investigator, make it undesirable for the patient to participate in the study. * Participant is unwilling to allow researchers to access their clinical notes and diagnostic scans. * Participant is unwilling to complete an experience questionnaire * The participant cannot speak or understand English. Exclusion Criteria MRL arm: * Any contraindications to MRI identified after MRI safety screening * Unable to tolerate MRI scanning * Uncontrolled pain/ poor pain control. * MSCC in the cervical spine. * More than one vertebral level of compression
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What it tests

  • Radiotherapy to the spine in a single appointment
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Where

1 site
The Christie NHS Foundation Trust
Manchester, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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