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Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study

Recruitingn/aAges 18 Years - 40 YearsAllNiguarda Hospital
NCT06965335 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Observational, retrospective and prospective multicentric Italian study of patients diagnosed with colorectal cancer between age 18-40, aiming at underpinning the biology of vEO-CRC, including colibactin as well as a broader proteo-genomic characterization, to identify potential new therapeutic targets specifically directed to this peculiar subset of patients.

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📋 Eligibility rules (as published)
1. Patients with diagnosis of colorectal cancer (vEO-CRC: 18-40 years of age), or SO-CRC diagnosed later than age 60; 2. Informed consent signature from alivepatient; 3. Availability of formalin-fixed paraffin embedded (FFPE) tumor samples (5 FFPE 4uM thick slides and 10 FFPE 10 uM thick slides) and/or fresh tumor tissue retrieved from a biopsy or surgical procedure performed as per clinical standard of care.
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What it tests

  • BIOLOGICAL STUDY aiming at describing clinicophatological features of EO-CRC vs SO-CRC
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Where

1 site
ASST Grande Ospedale Metropolitano Niguarda
Milan, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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