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โ† Trials
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Multiprofen-CC to Reduce Pain in Hand Arthritis

RecruitingPhase 3Ages 18 Years - anyAllSt. Joseph's Healthcare Hamilton
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In plain words

What the trial is, and whether it could suit you

This clinical trial aims to find out if using 1 gram of Multiprofen-CC cream on the hands three times a day for 4 weeks can help reduce pain in adults with hand osteoarthritis, compared to a placebo (a cream with no active medicine). The research team will also look at how Multiprofen-CC affects hand function, opioid use, and how patients feel about their overall improvement. In addition, the research team will keep track of any side effects. Participants will: * Use both Multiprofen-CC and a placebo (a cream with no active medicine) during the study, in a random order. * Be asked to apply 1 gram of cream to their hands three times a day for 2 weeks, following the manufacturer's instructions. * Attend a visit before starting the study, after 2 weeks, and after 6 weeks. * Report any symptoms they experience during the study.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults (18+) * Have been diagnosed with hand osteoarthritis according to American College of Rheumatology criteria * Experience pain and/or loss of function in one or both hands that interferes with daily life * Provide informed consent Exclusion Criteria: * Unable to consent * Unable or unwilling to follow study protocol * Known allergy or contraindication to any of the study drugs or their ingredients * Have open wounds/cuts and/or skin conditions on the hand area * Pregnant or breastfeeding * History of impaired kidney or liver function * Rheumatoid or other inflammatory arthropathy * Hand surgery within the past 6 months or planned within the study period. * Use daily opioids (other than short acting codeine) for a chronic pain condition other than hand arthritis
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What it tests

  • Multiprofen-CCโ„ข plus standard treatment
  • Placebo plus standard treatment
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Where

1 site
St. Joseph's Healthcare Hamilton
Hamilton, Canada
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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