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Varenicline for Smoking Reduction in Veterans Not Ready To Quit

RecruitingPhase 4Ages 21 Years - anyAllVA Office of Research and Development
NCT06966362 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In order to reduce the prevalence of cigarette smoking among Veterans, it is vital that healthcare providers offer effective tobacco treatment to all Veterans who smoke, including those not ready to make a quit attempt. Smoking treatments currently available to Veterans who are not ready to quit are only weakly effective. This project will generate new knowledge about the effectiveness of a promising varenicline-based intervention designed to increase quit attempts and long-term abstinence in Veterans who are initially not ready to quit. This project has great potential to engage Veterans not ready to quit smoking in treatment that increases quit attempts and quitting success, thereby reducing morbidity and mortality caused by smoking in Veterans.

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Report smoking an average of 5 or more cigarettes daily for the previous 6 months * Not ready to set a quit date in the next 30 days but willing to cut down on their smoking * Able to read, write, and speak English * Be medically eligible to use study medications (nicotine replacement therapy (NRT) or varenicline) * If female, use an approved method of birth control while using study medication * Be a Veteran Exclusion Criteria: * Unable to give informed, voluntary consent to participate * Current use of any pharmacotherapy for smoking cessation * Use of non-cigarette tobacco products as primary form of tobacco use * Incarceration
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What it tests

  • Motivation-Phase Varenicline
  • Motivation-Phase Nicotine Mini-Lozenge
  • Cessation-Phase Combination Nicotine Replacement Therapy (NRT)
  • Cessation-Phase Varenicline
  • Motivation-Phase Counseling
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Where

4 sites
VA San Diego Healthcare System, San Diego, CA
San Diego, United States
Minneapolis VA Health Care System, Minneapolis, MN
Minneapolis, United States
Durham VA Medical Center, Durham, NC
Durham, United States
William S. Middleton Memorial Veterans Hospital, Madison, WI
Madison, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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