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Nasopharyngeal Airway Combined With Nasal High-flow Oxygen Therapy During Painless Gastroscopy in Obesity Patients

RecruitingNAAges 18 Years - anyAllNanjing First Hospital, Nanjing Medical University
NCT06966934 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Gastroscopy is a commonly used, direct, and reliable method for screening and diagnosing digestive tract diseases. However, as an invasive examination, it can cause adverse reactions such as pain, nausea, vomiting, and choking cough in patients. Compared with ordinary gastroscopy, painless gastroscopy offers higher comfort and satisfaction for patients and greater convenience for endoscopists during operation. The most common complication of painless gastroscopy diagnosis and treatment is hypoxia. High-flow nasal cannulala (HFNC) provides a higher oxygen concentration and flow rate than an ordinary nasal catheter. It has the functions of heating and humidifying, which can relieve the pressure on the nasal mucosa cilia, keep the airway unobstructed and moist, and reduce the risk of epistaxis. Due to changes in airway anatomical structures such as fat accumulation in the head and neck and

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients undergoing painless gastroscopy; 2. Patients with an age greater than 18 years old; 3. American Society of Anesthesiologists (ASA) physical status classification from Grade I to Grade III; 4. Body Mass Index (BMI) greater than 28 kg/m² Exclusion Criteria: 1. Patients with contraindications to endoscopic procedures or those who refuse sedation/anesthesia; 2. Patients allergic to propofol, eggs, soybeans, milk, etc.; 3. Patients with gastrointestinal tract obstruction and gastric emptying disorders; 4. Patients with acute pharyngitis, tonsillitis, and upper respiratory tract infections; 5. Patients in the acute exacerbation stage of respiratory diseases such as asthma, bronchitis, and chronic obstructive pulmonary disease (COPD); 6. Patients with acute arrhythmia and those with severe heart diseases (congenital diseases, valvular diseases); 7. Patients with severe hepatic and renal insufficiency who require alternative treatment; 8. Patients with severe mental disorders who need medications to control their symptoms; 9. Patients with moderate or above anemia, abnormal coagulation function, and hematological diseases; 10. Patients with nasal cavity lesions leading to severe nasal congestion; 11. Pregnant and lactating patients.
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What it tests

  • NPA
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Where

1 site
Nanjing First Hospital
Nanjing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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