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Evaluation of the Safety of Terahertz Scanning System on Corneas

Recruitingn/aAges 21 Years - anyAllSingapore Eye Research Institute
NCT06967792 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This observational study aims to establish the safety profile of the use of Terahertz (THz) scanning system on corneal diseases. Participants with "non-seeing" eyes but normal corneas will undergo THz scanning. Eye examinations will be conducted at baseline, immediately after scanning, and at 1 day, 1 week, and 1 month post-scanning. These examinations will include measurements of visual acuity, eye structural, retinal health, corneal cell morphology, and corneal nerve status. The investigators hypothesize that the THz scanning system is safe for application to the human cornea.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Be at least 21 years of age * Regardless of gender (Male/Female) * Regardless of race (Chinese/Malay/Indian/Eurasian/Others) * Willingness and ability to follow all instructions and comply with study schedule for study visit * Have at least 1 eye (Study eye) that is deemed functionally blind but contain healthy corneas * Ability to hold face sufficiently stable to undergo necessary scans * Best Spectacle Corrected Visual Acuity (BSCVA) in the study eye of hand motion or worse Exclusion Criteria: * Pregnant/Breast-feeding women * Eyes with previous major surgery on the cornea such as corneal transplantation, refractive surgery, corneal cross-linking procedure * Eyes with previous infectious keratitis * Eyes with long-term use of glaucoma eye drops * Eyes with known moderate or server meibomian gland dysfunction * Eyes with active inflammation or infection, or chronic ocular surface inflammation * Systemic diseases that affect the ocular surface, such as systemic autoimmune diseases
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What it tests

  • Terahertz (THz) scanning using THz Imaging system.
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Where

1 site
Singapore National Eye Centre
Singapore, Singapore
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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