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Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain

RecruitingNAAges 18 Years - 60 YearsAllThe University of Texas Health Science Center, Hoโ€ฆ
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and to determine pressure pain ratings by using Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI), Transcranial Alternating Current Stimulation (tACS), sham and Transcranial random noise stimulation (tRNS)

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Meet the MRI / EEG screening criteria * Fluent in English Exclusion Criteria: * Current or history of major medical, neurological, or psychiatric illness based on self-report * History of cardiac, respiratory, or nervous system disease that, in the investigator's judgment, precludes participation in the study because of a heightened potential for adverse outcome (for example: asthma or claustrophobia) * History of head trauma * Pregnant or lactating * Presence of any contraindications to MRI scanning (for example: cardiac pacemaker, metal implants, claustrophobia, pregnancy, cannot lie still in fMRI scanner) * Conditions making study participation difficult (e.g., paralysis, psychoses, or other severe psychological problems as per the judgment of a study investigator during Session 1) * Active substance abuse disorders (based on subject self-report)
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What it tests

  • transcranial alternating current stimulation (tACS)
  • Sham
  • transcranial random noise stimulation (tRNS)
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Where

1 site
The University of Texas Health Science Center at Houston
Houston, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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