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A Study on the Correlation Between Oral Health and Delirium in Surgical Inpatients

Recruitingn/aAges 18 Years - 90 YearsAllXinhua Hospital, Shanghai Jiao Tong University Sc…
NCT06969092 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Delirium is a clinical syndrome characterized by acute attention deficits, altered consciousness, and fluctuating cognitive dysfunction, typically triggered by multifactorial causes such as physical illness, medication use, or postoperative stress . As the most common complication in hospitalized patients, delirium is highly prevalent among elderly surgical populations, with postoperative delirium (POD) occurring in 7.5%-27.5% of cases, and rates rising to 50%-70% in intensive care unit (ICU) patients . Its onset is closely associated with poor prognoses, including long-term postoperative cognitive decline , increased mortality, prolonged hospitalization, and elevated healthcare costs (annual costs in the United States ranging from 38billionto152 billion) . Early prevention and screening of POD are therefore critical to improving patient outcomes and reducing healthcare burdens. Surgica

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged ≥18 years scheduled for elective cardiac or thoracic surgery requiring endotracheal intubation. Patients without consciousness impairment, able to cooperate with the investigation. Patients or their legal guardians informed about the study's purpose, methodology, and content, with signed informed consent forms. Exclusion Criteria: * Patients with pre-existing oral conditions (e.g., xerostomia, oral mucosal lesions) prior to mechanical ventilation. Patients with a history of radiotherapy, chemotherapy, or corticosteroid use before surgery. Patients experiencing intraoperative mortality.
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What it tests

  • Oral Frailty
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Where

1 site
Shanghai Xinhua hospital
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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