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Improve the Strategies of Endoscopic and Interventional Treatment of Gastroesophageal Hemorrhage in Portal Hypertension

Recruitingn/aAges 18 Years - anyAllShanghai Zhongshan Hospital
NCT06970509 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Endoscopic esophageal variceal ligation combined with gastric variceal embolization using tissue glue is currently the first-choice method for preventing rebleeding in patients with cirrhosis and portal hypertension. However, the rebleeding rate remains relatively high. Factors such as extra-luminal vascular bundles in the esophagus and stomach walls, and portosystemic shunts significantly affect the therapeutic outcomes. Therefore, there is an urgent need to develop an individualized treatment model for esophagogastric varices based on the anatomical and hemodynamic characteristics of the varices, to stratify patient risks and provide tailored treatment options. Before the treatment of esophagogastric varices, the vascular characteristics of esophagogastric varices are assessed based on imaging data such as portal venous CT and ultrasound, as well as clinical information. Risk factors

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Confirmed diagnosis of portal hypertension; 2. Underwent imaging and endoscopic examination or treatment within one week after admission; 3. Endoscopy revealed the presence of esophageal and/or gastric varices. Exclusion Criteria: 1. CT image slice thickness does not meet the requirements or there are artifacts; 2. Endoscopy shows no presence of esophageal and/or gastric varices; 3. Presence of severe life-threatening diseases of the circulatory, hematological, or respiratory systems; 4. Lack of important historical medical information or other relevant data.
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What it tests

  • Not listed
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Where

10 sites
Southern Medical University Nanfang Hospital
Guangzhou, China
The Third Affiliated Hospital of Sun Yat-sen University
Guangzhou, China
The First Affiliated Hospital of Nanchang University
Nanchang, China
People's Liberation Army Northern Theater General Hospital
Shenyang, China
Qilu Hospital of Shandong University
Jinan, China
Shandong Provincial Hospital
Jinan, China
Renji Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, China
Shanghai Changzheng Hospital
Shanghai, China

…and 2 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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