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Wearable Sensors to Detect Atypical Muscle Activation in Young Infants

Recruitingn/aAges 0 Months - 8 WeeksAllShirley Ryan AbilityLab
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to see if wearable sensor technology can be used to evaluate muscle activity and/or identify atypical muscle tone in infants up to 48 weeks postmenstrual age (8 weeks corrected age). These sensors are placed on the surface of the skin and record data about a child's body movements and muscle activity.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * For Infants with low tone: * Hospitalized in the NICU * AND \>38 weeks post-menstrual age * AND abnormal normal brain imaging OR Apgar score \<7 at five minutes with umbilical cord pH (if obtained) \<7.15 * AND 2 or more warning signs for muscle tone or posture using the HNNE short form * AND legal guardian able and willing to give written consent and comply with study procedures * For Infants with typical tone: * Born at 38-41 weeks of gestation * AND hospitalized after birth in the NICU OR well newborn nursery * AND infants with appropriate for gestational age birth weight * AND HNNE exam (short proforma) normal with no warning signs for any parameter * AND legal guardian able and willing to give written consent and comply with study procedures. Exclusion Criteria: * Infants of Both Low Tone and Typical Tone Cohorts: * Missing or incomplete limbs (such as from amputation or congenital limb defects). * Open wounds or skin breakdown on the limbs or torso. * Presence of known genetic syndrome or congenital anomalies requiring surgery or affecting function * Use of sedative medications (may include phenobarbital if level stable and therapeutic) * Legal guardian unable to give written consent and comply with study procedures. * Does not receive medical clearance from a physician to participate in the study if the individual is receiving inpatient care.
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What it tests

  • Not listed
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Where

2 sites
Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, United States
Shirley Ryan AbilityLab
Chicago, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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