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Postoperative Pain Comparison of Two Root Canal Sealers in Irreversible Pulpitis

RecruitingPhase 2Ages 20 Years - 40 YearsAllArmed Forces Institute of Dentistry, Pakistan
NCT06975761 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study, approved by the Institutional Ethics Review Committee, AFID (Annex "A"), will involve 62 eligible patients from the Operative Dentistry Department, Armed Forces Institute of Dentistry. Patients (and their guardians) will receive a detailed explanation in Urdu, and written informed consent will be obtained (Annex "B"). Study Design: Randomized Controlled Trial: Patients will be randomly divided into two equal groups using a scientific random number table. Inclusion Screening: Includes medical history, clinical examination, periapical radiographs. Treatment Protocol: Root canal therapy under local anesthesia with rubber dam isolation. Working length determined using DentaPort ZX apex locator, confirmed with radiograph. Instrumentation: ProTaper Universal hand files up to F2 with 5.25% NaOCl irrigation. Patency confirmed with #10 K-file between each instrument change. F

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Permanent mandibular first molar with irreversible pulpitis without swelling and sinus. 2. Patients of male gender between 20-40 years of age. 3. Systemically healthy patients with no other co morbidity classified as ASA-I 4. Patients who agree to attend for re call appointments and provide a written consent Exclusion Criteria: \- 1. Teeth with calcified canals and previously treated teeth. 2. Mandibular molars with reversible pulpitis. 3. Pregnant and lactating mothers. 4. Patients who are immunocompromised, anxious, mentally ill. 5. Cases of root fracture. 6. Patients who consumed analgesics 12-24 hrs before primary root canal therapy. 7\. Patients who are allergic to any of the medications being tested.
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What it tests

  • Resin Based sealer
  • ZnO eugenol based sealers
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Where

1 site
Armed Forces Institute of Dentistry
Rawalpindi, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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