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PRIORITY-CONNECT 2 Trial

RecruitingNAAges 18 Years - anyAllSurgical Outcomes Research Centre (SOuRCe)
NCT06976710 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Objectives: The primary aim of this project is to establish the effectiveness of an individualised stepped, multidisciplinary intervention, including education and peer support group, delivered via a virtual multimodal (p)rehabilitation hub, in reducing postoperative complications within 30-days following colorectal cancer surgery, compared to usual care alone. The secondary aims will be to obtain data on the likely difference in key outcomes including: (i) Quality of life (EORTC QLQ-C30 and QLQ-CR29) (ii) Number of days at home within 30, 90 and 365 days after surgery (DAH-30, 90, 365) (iii) Quality of recovery (QoR-15) (iv) Cost-effectiveness (v) Implementation metrics (RE-AIM) Our hypothesis is that the PRIORITY-CONNECT 2 intervention will be more effective in reducing postoperative complications and more cost-effective than usual care. Study design: Pragmatic Randomised Type I

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged ≥18 years undergoing elective major surgery for colon or rectal cancer with curative intent * Consulting with a colorectal cancer surgeon at least 1 week prior to scheduled surgery Exclusion Criteria: * Patients undergoing Pelvic Exenteration (PE), Cytoreductive Surgery (CRS) with or without HIPEC, or concurrent surgery for metastatic disease * Cognitive impairment such that they are unable to provide informed consent
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What it tests

  • Preoperative Exercise
  • Postoperative Exercise
  • Preoperative Nutrition
  • Postoperative Nutrition
  • Preoperative Psychology
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Where

31 sites
Coffs Harbour Health Campus
Coffs Harbour, Australia
Calvary Mater Hospital
Newcastle, Australia
John Hunter Hospital
Newcastle, Australia
Chris O'Brien Lifehouse
Sydney, Australia
Royal Prince Alfred Hospital
Sydney, Australia
Concord Repatriation General Hospital
Sydney, Australia
Westmead Hospital
Sydney, Australia
Blacktown Hospital
Sydney, Australia

…and 23 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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