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Clinical Study on the Treatment of Herpes Zoster Pain With Dexmedetomidine Combined With Long-term High Voltage

RecruitingPhase 2Ages 40 Years - 85 YearsAllFenghui Deng
NCT06978192 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Participants will be invited to take part in clinical research. This informed consent form will provide information to the participants to help them decide whether to participate in the clinical study. If participants have any questions, please ask them directly to the researcher in charge of this study. This study was approved by the Biomedical Research Ethics Review Committee of the Institute. This trial is a randomized controlled clinical study. According to the different treatment methods, the control group was randomly divided into the control group and the experimental group. Control group: On the basis of conventional drug treatment, long-term high-voltage pulsed radiofrequency treatment was carried out. Experimental group: On the basis of conventional drug treatment, dexmedetomidine nasal spray was administered before HL-PRF treatment, before bedtime on the day of the operation,

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with adverse reactions that are not effective in conventional drug treatment and cannot tolerate drugs * The pain is located in the corresponding innervated are * The pain affects the patient's daily life or work * Diagnostic nerve block is effective and pain limited * Recurrent herpes zoster pain * Patients with shingle-related pain aged 40-85 years Exclusion Criteria: * Infection at the puncture site, systemic infection that may spread, and malignant tumors near the puncture * There are contraindications in minimally invasive interventional therapy such as coagulation function and platelet dysfunction * Allergies to local anesthetics and inhalants * Heart, lung, liver, kidney and other important organ failure, can not tolerate surgery * Severe endocrine system diseases or long-term use of hormone or immunosuppressive therapy * Patients with cardiac pacemakers, pregnant or lactating women * Patients with cognitive dysfunction or poor coordination * Patients who have been treated with electrical stimulation or PRF
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What it tests

  • dexmedetomidine nasal spray group
  • long duration high voltage pulse RF therapy group
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Where

1 site
Affiliated Hospital of Zunyi Medical University
Zunyi, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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