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Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia

RecruitingPhase 3Ages 21 Years - 60 YearsAllAl-Azhar University
NCT06979141 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this prospective randomized controlled double-blinded study is to compare the efficacy of dexmedetomidine, MgSO4 and lidocaine for cough suppression during general anesthetic emergence as regard number and severity.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Aged 21-60 years. * Both genders. * Body mass index \< 30 kg/ m2 * American Society of Anesthesiology (ASA) physical status I-II. * Mallampati score class I or II. * Patients undergoing surgery under general anesthesia. Exclusion Criteria: * Known allergy to study drugs. * History of psychiatric illness. * Patients with major organ diseases. * Pre-existing neurological deficits. * Body mass index \>30 kg/m2. * Active airway infection or history of tracheal and laryngeal surgery. * Lower esophageal sphincter incompetence (and reflux). * Increased intracranial and intraocular pressure. * Use of cough-inducing medications * Pregnant, and lactating women.
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What it tests

  • Dexmedetomidine
  • Magnesium sulfate
  • Lidocaine
  • normal saline
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Where

1 site
Faculty of Medicine, Al-Azhar university Assiut, Egypt.
Asyut, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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