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โ† Trials
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Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus

RecruitingPhase 2Ages any - anyAllCairo University
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In plain words

What the trial is, and whether it could suit you

Bromelain, an enzyme extract derived from pineapples, has shown promise due to its anti-inflammatory and wound-healing properties. However, its efficacy in treating oral mucosal ulcers remains unexplored. This study aims to provide clinical evidence on the efficacy of bromelain for managing OLP, potentially offering a safer and more effective treatment option.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients suffering from symptomatic OLP * Patients free from any visible oral lesions other than OLP. * Patients who agreed to take the supplied interventions. * Patient who will agree to participate in the study. * Patients who will accept to sign the informed consent. Exclusion Criteria: * Patients suffering from any systemic disease. * Treatment with any systemic treatment such as systemic steroids, other immunosuppressive drugs or non-steroidal anti-inflammatory drugs at least eight weeks. * Treatment with any oral topical medications for at least four weeks prior to the study. * Pregnant and lactating mothers.
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What it tests

  • Topical Bromelain
  • 0.1% topical triamcinolone acetonide
  • Combination of Topical Bromelain and Triamcinolone Acetonide in Orabase
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Where

1 site
Cairo University
Cairo, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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