SSTR2 Imaging With [68Ga]Ga-DOTA-TOC PET/CT in NPC

Inclusion Criteria: * Stage IB-IVA NPC (AJCC 9th edition), EBV positive determined by Epstein-Barr virus-encoded RNA (EBER). * Planned treatment with induction chemotherapy or CRT without induction chemotherapy. * Age ≥ 18 years. * Signed informed consent. * Willingness and ability to comply with all protocol required procedures. * Negative serum pregnancy test at screening in women of childbearing potential. * Archival tumor tissue available or consent to undergo a tumor biopsy procedure. Exclusion Criteria: * Previous treatment with chemotherapy or radiotherapy for NPC. * Treatment with any investigational agent or participation in another clinical trial with therapeutic intent within 28 days prior to \[68Ga\]Ga-DOTA-TOC injection. * Any other diseases, metabolic dysfunction, physical examination finding, or clinical laboratory finding giving reasonable suspicion of a disease or that may affect the interpretation of the results or render the patient at high risk from complications. * Altered mental status, or any psychiatric condition that would prohibit the understanding or rendering of informed consent. * Inability to lie in supine position for 25 minutes. * Patients who are pregnant or breastfeeding.