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Efficacy and Safety of Photodynamic Therapy for Cervical and Vaginal Intraepithelial Neoplasia

RecruitingNAAges 18 Years - 65 YearsFemalePeking University Third Hospital
NCT06982976 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To investigate the efficacy and safety of photodynamic therapy (20% 5-amino-ketovalerate 630nm red light) in the treatment of cervical and vaginal intraepithelial neoplasia in women in the real world.

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📋 Eligibility rules (as published)
Inclusion Criteria: * cervical/vaginal high-grade squamous intraepithelial lesions (HSILs) confirmed by colposcopy and pathological biopsy (CIN2 /CIN3 and/or VaIN2/ VaIN3) or persistent CIN1/VaIN1 lasting for more than one year with a strong willingness to treat; * colposcopy was adequate, and analysable colposcopy images were retained; * endocervical curettage (ECC) did not suggest higher-grade lesions. Exclusion Criteria: * coexistence or suspicion of cancer; * porphyria or suspected allergies to red and blue light; * severe medical comorbidities；
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What it tests

  • ALA-PDT
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Where

1 site
Peking Unniversity Third Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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