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Validation of the Use of Terahertz Scanning System on Corneal Scars and Corneal Edema

Recruitingn/aAges 21 Years - anyAllSingapore Eye Research Institute
NCT06983652 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This observational study aims to validate the use of THz scanning system in corneal edema and corneal scars, and to investigate the accuracy and performance on the use of THz scanning system in the evaluation of the progression of corneal edema and corneal scars. Participants corneal scars and corneal edema will undergo THz scanning, followed by a series of conventional clinical examinations for detailed characterization of the corneal lesion. The performance of the use of THz system on corneal scars and edema will be evaluated by correlating measurements from the THz scans with those obtained from standard clinical methods. The investigators hypothesize that the THz scanning system has the capacity to evaluate the hydration level on human corneas.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Be at least 21 years of age. * Regardless of gender (Male/Female). * Regardless of race (Chinese/Malay/Indian/Eurasian/Others). * Willingness and ability to follow all instructions and comply with study schedule for study visit. * Patients with corneal endothelial dysfunction (Fuchs' endothelial dystrophy or other causes of bullous keratopathy) at any disease stage OR Patients with corneal scars from any cause, with the absence of corneal edema. * Ability to hold face sufficiently stable to undergo necessary scans. Exclusion Criteria: * Eyes with active inflammation or infection, or chronic ocular surface inflammation * Unable to give consent * Physically immobile/poor instructional compliance * PI determined * Pregnant/ breast feeding women
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What it tests

  • THz scanning using THz Imaging system.
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Where

1 site
Singapore National Eye Centre
Singapore, Singapore
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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