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Comparing How Burn Wounds and Scars Heal in Children Using Chitosan and Silver Dressings

RecruitingNAAges 6 Months - 17 YearsAllMiloš Potkonjak
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In plain words

What the trial is, and whether it could suit you

Burns are among the most common types of trauma worldwide, ranking fourth after traffic accidents, falls, and violence, and account for an estimated 265,000 deaths annually (WHO). Most burn injuries result from heat exposure, though other causes include friction, chemicals, and electricity. Effective burn treatment aims to promote wound healing by supporting tissue regeneration and maintaining optimal conditions such as moisture, oxygenation, and low bacterial load. In Slovenia and across Europe, silver-based dressings are commonly used for burn care. While they are known to support wound healing, their effectiveness in reducing scar formation remains unclear. Chitosan-based hydrogels, by contrast, offer promising benefits due to their natural biocompatibility, antibacterial action, and support for tissue repair, though clinical data are still limited. This study aims to compare the ef

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age between 6 months and 17 years old 2. Having a first or second-degree superficial burn that does not require excision and grafting 3. Patients with a burn of less than 20% of the total body surface area (TBSA) 4. Admission within 72 hours of burn injury 5. First line of therapy is Burnshield® Dressing for the first 48 hours 6. Clean non-infected wound as diagnosed by the attending physician 7. Informed consent of the patient or caregiver Exclusion Criteria: 1. Causes other than contact burn, flame or scald injuries (i.e., electrical, chemical or frostbite) 2. Diabetes mellitus 3. Significant cardiac, pulmonary, or renal insufficiency 4. Severe hematologic disease, malignancy, hypo-immunity 5. Wounds noted to be contaminated or infected 6. Systemic inflammatory response syndrome (SIRS) or sepsis 7. Moderate or severe respiratory tract or lungs burn injuries 8. Previous treatment efforts such as previous debridement, silver sulfadiazine ointment or other topical agents (e.g.: oil, toothpaste, betadine, rivano) 9. Being pregnant or breastfeeding 10. Known sensitivity or allergy to one of the dressings or its components.
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What it tests

  • Chitosan-based dressing
  • Silver-based dressing
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Where

1 site
General Hospital Novo mesto
Novo Mesto, Slovenia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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